Brief introduction:
The On-line imaging probe for particle shape and size characterizationOn-line imaging probe for particle shape and size characterizationcan accurately measure the morphology and size of particles in real time, thereby deepening the understanding of the process, enabling optimized process control and production scale-up. The equipment is available in laboratory and industrial explosion-proof models.
Details:
An On-line imaging probe for particle shape and size characterization is essentially a microscope capable of online imaging and recording , enabling real-time and accurate measurement of particle morphology and size. This deepens understanding of the process and facilitates its optimization, control, and scale-up. Besides solid crystals, it also has extremely broad application prospects in characterizing other non-solid processes such as bubbles, foams, emulsions, droplets, polymers, and flow fields. On-line imaging probes for particle shape and size characterization are suitable for process research, product development, and improvement in production. They are particularly suitable for monitoring, optimizing, and controlling processes with high particle concentrations and the production of non-transparent particles.
On-line imaging probe function:
- Real-time capture of particle morphology and size changes during particle generation and growth.
- No sampling required; online recording of particle evolution and size distribution changes.
- Capturing the image of particles under challenging conditions (high concentration, opacity).
- Gaining instantaneous forms: gathering, dispersing, shattering, etc.
- Suitable for: crystallization, reaction, synthesis, granulation, disintegration, dissolution, agglomeration, bubble formation, emulsion, oil-liquid mixing, hydrate formation, etc.
Technical data
|
Measurement range |
1μm ~ 1000μm, customizable up to 10000μm (depending on lens magnification, camera, etc.) |
|
Measuring concentration |
Monitoring of solid particle concentration (related to particle shape) throughout the entire process. |
|
Measurement method |
Online measurement of crystal morphology, average size, and particle size distribution |
|
probe size |
Both sizes and diameters can be customized, suitable for experimental research and real-time monitoring of production processes. |
|
Operating temperature range |
-20 ℃ ~ 120℃ ( standard) - Higher temperatures are available. |
|
pressure |
Vacuum ~ 10 bar (standard), custom sizes up to 25 MPa |
|
Material |
Hastelloy (Standard) |
|
● Miniaturized instruments with online microscopy technology |
|
● Suitable for small reaction vessels, beakers, and piping systems. |
|
● Specially designed probes (camera /lens/light source) are widely applicable to many difficult systems ( especially non-transparent particulate systems and high solid concentrations). |
|
● Unique light source design effectively prevents particle deposition/adhesion onto the probe. |
|
● Different solutions (including gas cleaning systems) can be designed according to different material systems and customer requirements. |
|
● Powerful image processing capabilities enable multi-scale particle segmentation, calculation of particle shape parameters (principal element analysis and Fourier transform), cluster analysis, and quantitative product/process control. |
|
● The probe is corrosion-resistant and can measure samples with a pH range of 1 to 12. |
|
● Allows you to freely set the video capture time |
|
● Automatically records data, improving work efficiency |
|
● It can analyze graphs and provide particle size distribution in real time online. |
|
● No sampling, dilution, or sample preparation required. |
Real-time online particle size distribution analysis
On-line imaging probe for particle shape and size characterizationOn-line imaging probe for particle shape and size characterization (Pharmavision)are suitable for the following applications:
- Controlling crystal size and shape distribution
- Developing crystallization processes using solubility and metastable zone width (MSZW)
- Research and optimization of adding seed crystals during the crystallization process
- Observe and characterize phase separation (oil extraction).
- Directly observe how scaling up changes crystallization behavior
- Crystallization antisolvents are used to control crystal size and number.
- Optimize oil-water separation
- Research on droplet homogenization, grinding , and formulation
- Solving common crystallization problems in the laboratory
Complete recording of the crystallization process of glutamic acid samples
Clear images of the crystallization process of chemical materials
Real-time online observation of insoluble two-phase dispersed droplets